ADHD causes: Knowing fact from fiction

Parents, patients, and food are not at fault

Attention-deficit/hyperactivity disorder (ADHD; formerly known as ADD) definitely impairs brain function, but no one knows for sure what causes it.1,2

The possible role of genetics in ADHD

You may have been wondering, is ADHD genetic? Well, studies have shown that ADHD tends to run in families and is probably inherited.1,2

  • More than 20 scientific studies have shown a strong genetic connection to ADHD1
  • About 80% of ADHD symptoms are genetic, and not related to family environment3

ADHD is not caused by2,3:

  • Anything the person with the condition or his or her parents did wrong
  • Food allergies
  • Eating too much sugar
  • Lack of discipline
  • Laziness
  • Lack of motivation

Other ADHD myths that can interfere with diagnosis and treatment include the idea that ADHD isn't real, ADHD is just behavioral and doesn't need medicine, and ADHD symptoms are always outgrown.

Knowing the ADHD facts and addressing these misperceptions will help many families move forward with treatment.

References: 1. National Resource Center on ADHD: A program of CHADD. What we know 1. The disorder named ADHD. http://www.help4adhd.org. Updated February 2008. Accessed May 23, 2016. 2. Centers for Disease Control and Prevention. Facts about ADHD. http://www.cdc.gov/ncbddd/adhd/facts.html. Accessed May 23, 2016. 3. National Resource Center on ADHD: A program of CHADD. Myths and misunderstandings. http://www.chadd.org/Understanding-ADHD/about-attention-deficit-hyperactivity-disorder/Myths-and-Misunderstandings.aspx. Accessed May 23, 2016.

IMPORTANT SAFETY INFORMATION

Evekeo (amphetamine sulfate tablets, USP) is a federally controlled substance (CII) with a high risk of abuse or dependence. Keep in a safe place to prevent misuse and abuse. Selling or sharing Evekeo may harm others and is illegal.

INDICATION

Evekeo® (amphetamine sulfate tablets, USP) is a prescription medicine for the treatment of narcolepsy, attention deficit disorder with hyperactivity as an integral part of a total treatment program and exogenous obesity as a short term adjunct in a regimen of weight reduction.

IMPORTANT SAFETY INFORMATION

Evekeo (amphetamine sulfate tablets, USP) is a federally controlled substance (CII) with a high risk of abuse or dependence. Keep in a safe place to prevent misuse and abuse. Selling or sharing Evekeo may harm others and is illegal.

Do not take Evekeo if you or your child:

  • has a history of advanced heart disease or hardening of the arteries, moderate to severe high blood pressure, hyperthyroidism, known hypersensitivity or other serious cardiac problems that may place you or your child at increased vulnerability to the sympathomimetic effects of a stimulant drug
  • is very anxious, tense or agitated
  • has a history of drug abuse
  • is taking or has taken within the past 14 days an anti-depression medicine called a monoamine oxidase inhibitor (MAOI)
  • is sensitive to, allergic to, or had a reaction to other stimulant medicines

Warnings and Precautions

Serious heart problems can occur when taking stimulant medicines, such as Evekeo, and can include:

  • sudden death in people who have heart problems or heart defects
  • sudden death, stroke and heart attack in adults
  • increased blood pressure and heart rate

Tell your doctor if you or your child has any heart problems including heart defects, abnormal heart rhythm, high blood pressure, disease known as cardiomyopathy, coronary artery disease, or a family history of these problems or sudden cardiac death. Call your doctor right away if you or your child has any signs of heart problems such as chest pain, shortness of breath or fainting while taking Evekeo.

Mental (psychiatric) problems can occur including:

  • new or worse behavior and thought problems
  • new or worse bipolar illness
  • new or worse aggressive behavior or hostility

New aggressive behavior or psychotic symptoms can occur in children and teenagers such as:

  • seeing things or hearing voices
  • believing things that are not true
  • being suspicious
  • new manic problems

Tell your doctor about any drug abuse, alcohol abuse or mental problems that you or your child has had or about a family history of suicide, bipolar illness or depression, new or worsening aggressive behavior or hostility. Call your doctor right away if you or your child has any new or worsening mental symptoms while taking Evekeo.


Circulation problems in fingers and toes:

  • fingers or toes may feel numb, cool, painful
  • fingers or toes may change color from pale, to blue, to red

Tell your doctor if you or your child has any numbness, pain, color change, or sensitivity to temperature in your fingers and toes or a family history of health conditions including circulation problems in fingers and toes. Call your doctor right away if you or your child has any signs of unexplained wounds appearing on fingers and toes while taking Evekeo.


Evekeo may cause serious side effects including:

  • slowing of growth (height and weight) in children, seizures, eyesight changes or blurred vision, and serotonin syndrome. Serotonin syndrome can be life threatening and happens when Evekeo is taken with certain medicines. Symptoms include agitation, hallucinations, coma or other changes in mental status, problems controlling your movements or muscle twitching, fast heartbeat, high or low blood pressure, sweating or fever, nausea or vomiting, diarrhea, and muscle stiffness or tightness

The most common side effects reported with Evekeo include:

  • headache, stomach ache, trouble sleeping, decreased appetite, unpleasant taste, nervousness, dizziness, sexual problems (impotence in males), vomiting, itching, diarrhea or constipation, dry mouth, weight loss, and mood swings

Talk to your doctor if you or your child have side effects that are bothersome or do not go away, if you or your child is pregnant, plan on becoming pregnant, or are breast-feeding, about all health conditions (or a family history of), and about the medicines you or your child take. Your doctor will decide whether Evekeo can be taken with other medicines and if Evekeo is right for your child.

For additional safety information, consult the Evekeo full Prescribing Information and Medication Guide.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.